SCHEMBL738763

SCHEMBL738763

Clc1ccccc1OB(Oc1ccccc1Cl)Oc1ccccc1Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.45
LMNA P02545 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
DPP4 P27487 1/20 0.44
HPGD P15428 2/20 0.39
SLC6A4 P31645 3/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
SLC6A2 P23975 2/20 0.38
SLC6A3 Q01959 2/20 0.38
ALDH1A1 P00352 2/20 0.37
MEN1 O00255 1/20 0.37
PKM P14618 1/20 0.37
KMT2A Q03164 1/20 0.37
MAPT P10636 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
HTT P42858 1/20 0.37
CXCL8 P10145 1/20 0.37
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35
KCNH2 Q12809 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2885055 0.80 LMNA (0.42) TSHRLMNASMN1; SMN2HPGDSLC6A4
Potassium SCHEMBL8009526 0.78 LMNA (0.41) TSHRLMNASMN1; SMN2HPGDSLC6A4
SCHEMBL1436765 0.75 HPGD (0.59) TSHRLMNASMN1; SMN2DPP4HPGD
SCHEMBL7769417 0.75 TSHR (0.53) TSHRLMNASMN1; SMN2DPP4HPGD
SCHEMBL10935253 0.72
SCHEMBL12541 0.70
SCHEMBL19374664 0.70
SCHEMBL15336732 0.70
SCHEMBL5014006 0.70
SCHEMBL10400374 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2429957-B1 TAGGED SCALE INHIBITORS ABSOLUTE PETRO HYDRO TECH CO LTD (CN) 2015-07-29 EP disclosed
EP-2429957-A1 TAGGED SCALE INHIBITORS Absolute Petro Hydro Tech Co. Ltd (CN) 2012-03-21 EP disclosed
US-7888417-B2 core or the layer includes a composition formed from a base polymer, a crosslink initiator, and at least one additive; additive has at least one carbon-oxygen-boron linkage, carbon in the linkage being a secondary or tertiary carbon; enhances coefficient of restitution and/or reduces compression of core ACUSHNET COMPANY (US) 2011-02-15 US disclosed
WO-2010128322-A1 TAGGED SCALE INHIBITORS ABSOLUTE PETRO HYDRO TECH CO. LTD (CN) 2010-11-11 WO disclosed
US-20090069271-A1 WOOD TREATMENT STANIMIROFF IVAN LAURENCE 2009-03-12 US disclosed
US-20080261722-A1 COMPOSITIONS FOR USE IN GOLF BALLS ACUSHNET COMPANY 2008-10-23 US disclosed
US-20080227567-A1 COMPOSITIONS FOR USE IN GOLF BALLS ACUSHNET COMPANY 2008-09-18 US disclosed
US-20080176678-A1 Compositions for Use in Golf Balls ACUSHNET COMPANY 2008-07-24 US disclosed
EP-1945424-A1 WOOD TREATMENT Stanimiroff, Ivan Laurence (NZ) 2008-07-23 EP disclosed
US-7361711-B2 Compositions for use in golf balls ACUSHNET COMPANY (US) 2008-04-22 US disclosed
WO-2007055601-A1 WOOD TREATMENT STANIMIROFF IVAN LAURENCE (NZ) 2007-05-18 WO disclosed
US-20060281586-A1 Compositions for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2006-12-14 US disclosed
US-20060281587-A1 Compositions for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2006-12-14 US disclosed
US-20050245652-A1 Compositions for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-11-03 US disclosed
US-20050245657-A1 Compositions for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-11-03 US disclosed
US-4281173-A Preparation of unsaturated diesters by catalytic oxidative carbonylation of diolefins ATLANTIC RICHFIELD COMPANY (US) 1981-07-28 US disclosed
US-4195184-A Preparation of unsaturated monoesters by catalytic oxidative carbonylation of diolefins ATLANTIC RICHFIELD COMPANY (US) 1980-03-25 US disclosed
US-4189599-A Preparation of dimethyl adipate by the hydrogenation of dimethyl hex-3-endioate ATLANTIC RICHFIELD COMPANY (US) 1980-02-19 US disclosed
US-4171450-A Preparation of unsaturated diesters by catalytic oxidative carbonylation of diolefins ATLANTIC RICHFIELD COMPANY (US) 1979-10-16 US disclosed
US-4041068-A AS CATALYST A PALLADIUM, PLATINUM OR RHODIUM SALT WITH AN AMINE AND AN ALCOHOL ATLANTIC RICHFIELD COMPANY (US) 1977-08-09 US disclosed