Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431775 | 0.87 | MAOA (0.41) | SMYD2 | |
| SCHEMBL7386864 | 0.86 | TLR8 (0.33) | — | |
| SCHEMBL7429083 | 0.85 | SMYD2 (0.30) | SMYD2 | |
| SCHEMBL7393343 | 0.83 | BACE1 (0.35) | — | |
| SCHEMBL8629817 | 0.83 | — | — | |
| SCHEMBL7398238 | 0.82 | GAA (0.34) | SMYD2 | |
| SCHEMBL4822404 | 0.79 | PDCD1 (0.34) | SMYD2 | |
| SCHEMBL7390456 | 0.74 | PDF (0.39) | — | |
| SCHEMBL8630245 | 0.72 | PDF (0.33) | — | |
| SCHEMBL7389531 | 0.71 | MAOA (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592791-A2 | Tricyclic compounds and peptide derivatives thereof | F. HOFFMANN-LA ROCHE AG (CH) | 1994-04-20 | — | — | EP | disclosed |