Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | Q9HBH1 | 1/20 | 0.33 | |
| ▸ | CDC25A | P30304 | 11/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7386864 | 0.87 | TLR8 (0.33) | PDFCDC25AMEN1KMT2APPARG | |
| SCHEMBL7429083 | 0.87 | SMYD2 (0.30) | — | |
| SCHEMBL7390456 | 0.86 | PDF (0.39) | PDFMEN1KMT2A | |
| SCHEMBL7392958 | 0.84 | CDC25A (0.39) | CDC25ACES1 | |
| SCHEMBL8627860 | 0.82 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL7394625 | 0.74 | PDF (0.53) | PDFCDC25ACES1 | |
| SCHEMBL8631941 | 0.73 | PDF (0.33) | PDFCDC25ACES1MEN1KMT2A | |
| SCHEMBL875044 | 0.73 | BACE1 (0.39) | MEN1KMT2A | |
| SCHEMBL8633026 | 0.72 | BACE1 (0.40) | — | |
| SCHEMBL7388124 | 0.72 | SMYD2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811389-A | INHIBITING PLATELET AGGREGATION; BLOOD DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1998-09-22 | — | — | US | disclosed |
| US-5811548-A | USEFUL AS RESEARCH TOOLS IN THE DETERMINATION OF BIOLOGICALLY ACTIVE PEPTIDE SEQUENCES | HOFFMANN-LA ROCHE INC. (US) | 1998-09-22 | — | — | US | disclosed |