Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 2/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7388363 | 0.90 | CACNA1B (0.55) | CACNA1BFAAHCYP3A4CYP2D6TSHR | |
| SCHEMBL7389383 | 0.82 | CACNA1B (0.54) | CACNA1BFAAHCYP3A4CYP2D6TSHR | |
| SCHEMBL7391823 | 0.81 | CACNA1B (0.52) | CACNA1BFAAHCYP3A4CYP2D6TSHR | |
| SCHEMBL7391826 | 0.81 | CACNA1B (0.54) | CACNA1BFAAHCYP3A4CYP2D6TSHR | |
| SCHEMBL13932368 | 0.80 | SLC6A3 (0.49) | CACNA1BFAAHCYP3A4CYP2D6TSHR | |
| SCHEMBL7387813 | 0.80 | CACNA1B (0.55) | CACNA1BFAAHCYP3A4CYP2D6TSHR | |
| SCHEMBL7664030 | 0.79 | CACNA1B (0.67) | CACNA1BFAAHCYP3A4CYP2D6TSHR | |
| SCHEMBL7387826 | 0.79 | CACNA1B (0.60) | CACNA1BFAAHCYP3A4CYP2D6TSHR | |
| SCHEMBL3231137 | 0.77 | LMNA (0.62) | TSHRRAB9AKMT2AHTTLMNA | |
| SCHEMBL7668236 | 0.76 | CACNA1B (0.64) | CACNA1BFAAHCYP3A4CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999055688-A1 | SUBSTITUTED DIARYLALKYL AMIDES AS CALCIUM CHANNEL ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1999-11-04 | — | — | WO | disclosed |