Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8262020 | 0.83 | FAAH (0.45) | SLC6A3CACNA1BFAAHCYP3A4CYP2D6 | |
| SCHEMBL8262130 | 0.82 | SLC6A3 (0.46) | SLC6A3CACNA1BFAAHCYP3A4CYP2D6 | |
| SCHEMBL8260134 | 0.82 | SLC6A3 (0.46) | SLC6A3CACNA1BFAAHCYP3A4CYP2D6 | |
| SCHEMBL7388246 | 0.80 | CACNA1B (0.55) | SLC6A3CACNA1BFAAHCYP3A4CYP2D6 | |
| SCHEMBL4464147 | 0.78 | SLC6A3 (0.58) | SLC6A3RAB9AHDAC3HDAC1HDAC6 | |
| SCHEMBL7389383 | 0.77 | CACNA1B (0.54) | SLC6A3CACNA1BFAAHCYP3A4CYP2D6 | |
| SCHEMBL67664 | 0.77 | TBXA2R (0.65) | SLC6A3CACNA1BFAAHCYP3A4CYP2D6 | |
| SCHEMBL4475302 | 0.76 | EPHX2 (0.53) | SLC6A3HDAC6KCNH2 | |
| SCHEMBL4472878 | 0.76 | KCNH2 (0.59) | SLC6A3HDAC3HDAC1HDAC6MEN1 | |
| SCHEMBL4462497 | 0.76 | EPHX2 (0.49) | SLC6A3RAB9AHDAC6LMNAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7511077-B2 | Diamine calcium channel blockers | NEUROMED PHARMACEUTICALS LTD. (CA) | 2009-03-31 | — | — | US | disclosed |