Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 4/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | HTR7 | P34969 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.41 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9005366 | 0.98 | PDE10A (0.46) | PDE10ADRD4HTR1AHTR2AHTR7 | |
| SCHEMBL4635254 | 0.78 | PTPN11 (0.45) | PDE10ADRD4HTR1AHTR2AHTR7 | |
| SCHEMBL12683431 | 0.77 | CNR2 (0.46) | PDE10ADRD4HTR1AHTR2AHTR7 | |
| SCHEMBL22129422 | 0.77 | PDE10A (0.50) | PDE10ADRD4HTR1AHTR2AHTR7 | |
| SCHEMBL22129474 | 0.77 | PDE10A (0.46) | PDE10ADRD4HTR1AHTR2AHTR7 | |
| SCHEMBL21262167 | 0.73 | CHRNB2 (0.59) | PDE10ADRD4HTR1AHTR2AHTR7 | |
| SCHEMBL21262008 | 0.73 | CHRNB2 (0.59) | PDE10ADRD4HTR1AHTR2AHTR7 | |
| SCHEMBL20283148 | 0.73 | GRM4 (0.46) | PDE10ADRD4HTR1AHTR2AHTR7 | |
| SCHEMBL22153203 | 0.73 | PDE10A (0.46) | PDE10ADRD4HTR1AHTR2AHTR7 | |
| SCHEMBL21135741 | 0.73 | PDE10A (0.56) | PDE10ADRD4CNR2DRD2DEGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591030-A2 | 1-Heteroaryl-azetidines and -pyrrolidines as 5-HT3 agonists | SANOFI (FR) | 1994-04-06 | — | — | EP | disclosed |