Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 18/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7389350 | 1.00 | ITGB3 (0.41) | ITGB3ITGA2BALOX15F10PRSS1 | |
| Hydrochloric Acid SCHEMBL7390520 | 0.87 | ITGB3 (0.42) | ITGB3ITGA2BALOX15F10PRSS1 | |
| SCHEMBL7394701 | 0.81 | ITGB3 (0.41) | ITGB3ITGA2BALOX15F10PRSS1 | |
| SCHEMBL7394704 | 0.81 | ITGB3 (0.41) | ITGB3ITGA2BALOX15F10PRSS1 | |
| SCHEMBL8863305 | 0.81 | ITGB3 (0.43) | ITGB3ITGA2BALOX15 | |
| SCHEMBL7392878 | 0.79 | ITGB3 (0.40) | ITGB3ITGA2BALOX15 | |
| SCHEMBL7398264 | 0.79 | ITGB3 (0.40) | ITGB3ITGA2BALOX15 | |
| SCHEMBL7392883 | 0.79 | ITGB3 (0.40) | ITGB3ITGA2BALOX15 | |
| Hydrochloric Acid SCHEMBL8564618 | 0.76 | ACHE (0.40) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8569741 | 0.76 | DGAT1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587134-A2 | Cyclic urea derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1994-03-16 | — | — | EP | claimed |
| US-5880284-A | HAVING ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASES-INHIBITING EFFECTS | DR. KARL THOMAE GMBH (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5681841-A | PREVENTION CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1997-10-28 | — | — | US | disclosed |
| EP-0587134-A2 | Cyclic urea derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1994-03-16 | — | — | EP | disclosed |