Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7389513 | 0.80 | HTR7 (0.48) | HTR7MEN1KMT2AHTR2A | |
| SCHEMBL7389746 | 0.80 | HTR7 (0.60) | HTR7MEN1KMT2AEPHX2HTR2A | |
| SCHEMBL7392237 | 0.79 | HTR7 (0.58) | HTR7MEN1KMT2AEPHX2HTR2A | |
| SCHEMBL7386280 | 0.77 | HTR7 (0.56) | HTR7MEN1KMT2AEPHX2HTR2A | |
| SCHEMBL7388770 | 0.77 | HTR7 (0.56) | HTR7MEN1KMT2AEPHX2HTR2A | |
| Hydrochloric Acid SCHEMBL7388430 | 0.75 | HTR7 (0.46) | HTR7MEN1KMT2AEPHX2HTR2A | |
| SCHEMBL7392453 | 0.73 | ALDH1A1 (0.43) | HTR7MEN1KMT2ASIGMAR1 | |
| SCHEMBL7390164 | 0.73 | ALDH1A1 (0.43) | HTR7MEN1KMT2AHTR2ASIGMAR1 | |
| SCHEMBL11530025 | 0.73 | KMT2A (0.82) | HTR7MEN1KMT2AEPHX2SIGMAR1 | |
| SCHEMBL7390405 | 0.72 | HTR1A (0.55) | HTR7KMT2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864039-A | THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0873990-A1 | BENZOIC ACID COMPOUNDS AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-10-28 | — | — | EP | disclosed |