Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.37 |
| ▸ | CNR2 | P34972 | 4/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7390768 | 0.91 | KDM4E (0.42) | CNR1PTGER4CNR2KDM4EL3MBTL1 | |
| SCHEMBL8499206 | 0.88 | CNR1 (0.36) | CNR1PTGER4CNR2MEN1GFER | |
| SCHEMBL7390111 | 0.88 | PTGER4 (0.34) | CNR1PTGER4MEN1KMT2AKDM4E | |
| SCHEMBL8496443 | 0.87 | L3MBTL1 (0.36) | CNR1PTGER4CNR2MEN1GFER | |
| SCHEMBL5667865 | 0.84 | L3MBTL1 (0.42) | CNR1PTGER4CNR2MEN1GFER | |
| SCHEMBL27583491 | 0.84 | L3MBTL1 (0.42) | CNR1PTGER4CNR2MEN1GFER | |
| SCHEMBL8498353 | 0.81 | PPARG (0.37) | CNR1PTGER4MEN1KMT2AKDM4E | |
| SCHEMBL8501454 | 0.80 | TRPA1 (0.50) | CNR2MEN1KMT2ANPC1 | |
| SCHEMBL5669691 | 0.79 | KDM4E (0.38) | CNR1PTGER4CNR2KDM4EL3MBTL1 | |
| SCHEMBL7389876 | 0.79 | PTGER4 (0.37) | CNR1PTGER4CNR2EGLN1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877197-A | C-terminal modified (N-substituted)-2-indolyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases | CONATUS PHARMACEUTICALS, INC. | 1999-03-02 | — | — | US | disclosed |
| US-5869519-A | USE OF SUCH COMPOSITIONS IN THE TREATMENT OF PATIENTS SUFFERING INFLAMMATORY, AUTOIMMUNE AND NEURODEGENERATIVE DISEASES, FOR THE PREVENTION OF ISCHEMIC INJURY, AND FOR THE PRESERVATION OF ORGANS THAT ARE TO UNDERGO A TRANSPLANTATION | IDUN PHARMACEUTICALS, INC. (US) | 1999-02-09 | — | — | US | disclosed |