Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8496443 | 0.90 | L3MBTL1 (0.36) | CNR1MEN1KMT2AGFERCNR2 | |
| SCHEMBL7390768 | 0.89 | KDM4E (0.42) | CNR1CNR2TSHRPTGER4KDM4E | |
| SCHEMBL7389883 | 0.88 | CNR1 (0.38) | CNR1MEN1KMT2AGFERCNR2 | |
| SCHEMBL7200874 | 0.85 | CASP3 (0.40) | — | |
| SCHEMBL5667865 | 0.81 | L3MBTL1 (0.42) | CNR1MEN1KMT2AGFERCNR2 | |
| SCHEMBL27583491 | 0.81 | L3MBTL1 (0.42) | CNR1MEN1KMT2AGFERCNR2 | |
| SCHEMBL8499200 | 0.79 | MEN1 (0.36) | CNR1MEN1KMT2AGFERCNR2 | |
| SCHEMBL5670832 | 0.79 | CASP3 (0.44) | — | |
| SCHEMBL8498353 | 0.79 | PPARG (0.37) | CNR1MEN1KMT2ATSHRPTGER4 | |
| SCHEMBL7390111 | 0.79 | PTGER4 (0.34) | CNR1MEN1KMT2APTGER4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877197-A | C-terminal modified (N-substituted)-2-indolyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases | CONATUS PHARMACEUTICALS, INC. | 1999-03-02 | — | — | US | disclosed |