Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7387889 | 0.99 | DRD3 (0.53) | DRD3SLC6A2SLC6A4DRD2ADRA1A | |
| SCHEMBL7392760 | 0.82 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2TSHRNPSR1KMT2A | |
| SCHEMBL7394195 | 0.81 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2TSHRNPSR1MEN1 | |
| SCHEMBL7391407 | 0.81 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2TSHRNPSR1KMT2A | |
| SCHEMBL7390483 | 0.80 | KDM4E (0.50) | DRD3DRD2ABCB1ALDH1A1TSHR | |
| SCHEMBL7387357 | 0.80 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2TSHRNPSR1MEN1 | |
| SCHEMBL7387064 | 0.79 | KDM4E (0.49) | DRD3DRD2ABCB1ALDH1A1TSHR | |
| SCHEMBL7392969 | 0.78 | USP2 (0.55) | ALDH1A1MEN1KMT2ALMNAHRH3 | |
| SCHEMBL7387330 | 0.77 | MEN1 (0.55) | ALDH1A1MEN1KMT2ALMNAHRH3 | |
| SCHEMBL11128794 | 0.76 | DRD3 (0.69) | DRD3SLC6A2SLC6A4DRD2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864039-A | THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0873990-A1 | BENZOIC ACID COMPOUNDS AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-10-28 | — | — | EP | disclosed |