Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 5/20 | 0.69 |
| ▸ | DRD2 | P14416 | 5/20 | 0.67 |
| ▸ | HTR1A | P08908 | 3/20 | 0.67 |
| ▸ | HTR2A | P28223 | 3/20 | 0.67 |
| ▸ | HRH1 | P35367 | 3/20 | 0.67 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.67 |
| ▸ | HTR7 | P34969 | 1/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11169726 | 0.83 | HTR1A (0.56) | DRD3DRD2HTR1AHTR2AHRH1 | |
| SCHEMBL11166934 | 0.81 | HTR1A (0.54) | DRD3DRD2HTR1AHTR2AHRH1 | |
| SCHEMBL11280762 | 0.81 | DRD3 (0.56) | DRD3DRD2HTR1AHTR2AHRH1 | |
| SCHEMBL11161966 | 0.79 | HTR1A (0.52) | DRD3DRD2HTR1AHTR2AHRH1 | |
| SCHEMBL11181791 | 0.78 | HTR1A (0.51) | DRD3DRD2HTR1AHTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL11167530 | 0.78 | HTR1A (0.54) | DRD3DRD2HTR1AHTR2AHRH1 | |
| SCHEMBL11198528 | 0.78 | ALDH1A1 (0.60) | HTR1AMAPTTDP1 | |
| SCHEMBL29314713 | 0.78 | SIGMAR1 (0.71) | DRD3DRD2HTR1AHTR2AHRH1 | |
| SCHEMBL11166237 | 0.78 | HTR1A (0.50) | DRD3DRD2HTR1AHTR2AHRH1 | |
| SCHEMBL11219235 | 0.78 | HRH1 (0.80) | DRD3DRD2HTR1AHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58024563-A | — | — | None | — | — | JP | disclosed |
| JP-S5824563-A | (OMEGA-PIPERAZINYLALKOXY)POLYALKOXYBENZENE DERIVATIVE AND ITS ACID ADDITION SALT | MITSUBISHI CHEM IND LTD | 1983-02-14 | — | — | JP | disclosed |