Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | EBP | Q15125 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7390483 | 0.99 | KDM4E (0.50) | KDM4EEBPSIGMAR1TMEM97ABCB1 | |
| SCHEMBL7385165 | 0.81 | ALDH1A1 (0.53) | SIGMAR1ABCB1ALDH1A1TSHRDRD2 | |
| SCHEMBL7387889 | 0.81 | DRD3 (0.53) | ABCB1ALDH1A1TSHRLMNADRD2 | |
| SCHEMBL7389275 | 0.81 | MAOB (0.45) | SIGMAR1ABCB1ALDH1A1TSHR | |
| SCHEMBL7391448 | 0.80 | SIGMAR1 (0.53) | SIGMAR1ABCB1ALDH1A1TSHRDRD2 | |
| SCHEMBL7383386 | 0.79 | MAOB (0.43) | SIGMAR1ABCB1ALDH1A1TSHR | |
| SCHEMBL7390495 | 0.79 | DRD3 (0.52) | ABCB1ALDH1A1TSHRLMNADRD2 | |
| SCHEMBL7391532 | 0.79 | GBA1 (0.54) | SIGMAR1DRD2DRD3 | |
| SCHEMBL27337543 | 0.78 | SIGMAR1 (0.64) | EBPSIGMAR1TMEM97 | |
| SCHEMBL7389363 | 0.78 | HRH3 (0.51) | SIGMAR1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864039-A | THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0873990-A1 | BENZOIC ACID COMPOUNDS AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-10-28 | — | — | EP | disclosed |