Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7393692 | 0.98 | SIGMAR1 (0.47) | SIGMAR1KEAP1SMN1; SMN2ALOX15CYP2D6 | |
| SCHEMBL7386349 | 0.98 | SIGMAR1 (0.47) | SIGMAR1KEAP1SMN1; SMN2ALOX15CYP2D6 | |
| SCHEMBL4018537 | 0.98 | SIGMAR1 (0.47) | SIGMAR1KEAP1SMN1; SMN2ALOX15CYP2D6 | |
| SCHEMBL7373475 | 0.93 | KEAP1 (0.54) | SIGMAR1KEAP1SMN1; SMN2ALOX15CYP2D6 | |
| SCHEMBL4543044 | 0.82 | — | — | |
| SCHEMBL1615517 | 0.82 | ALOX15 (0.61) | SIGMAR1KEAP1SMN1; SMN2ALOX15CYP2D6 | |
| SCHEMBL4666999 | 0.82 | — | — | |
| SCHEMBL1614410 | 0.79 | ALOX15 (0.58) | SIGMAR1KEAP1SMN1; SMN2ALOX15 | |
| SCHEMBL1615521 | 0.79 | ALOX15 (0.58) | SIGMAR1KEAP1SMN1; SMN2ALOX15 | |
| SCHEMBL1614431 | 0.79 | ALOX15 (0.58) | SIGMAR1KEAP1SMN1; SMN2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864039-A | THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0873990-A1 | BENZOIC ACID COMPOUNDS AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-10-28 | — | — | EP | disclosed |