Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 9/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.63 |
| ▸ | F2 | P00734 | 1/20 | 0.63 |
| ▸ | F10 | P00742 | 1/20 | 0.63 |
| ▸ | PLG | P00747 | 1/20 | 0.63 |
| ▸ | PLAU | P00749 | 1/20 | 0.63 |
| ▸ | PLAT | P00750 | 1/20 | 0.63 |
| ▸ | HPN | P05981 | 1/20 | 0.63 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.63 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13522926 | 0.91 | HDAC6 (0.70) | AMY1AKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL7393988 | 0.88 | F7 (0.55) | AMY1AKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL7396100 | 0.85 | AMY1A (0.64) | AMY1AKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL31429538 | 0.85 | AMY1A (0.64) | AMY1AKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL31559156 | 0.83 | AMY1A (0.66) | AMY1AKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL7389359 | 0.83 | AMY1A (0.66) | AMY1AKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL13492665 | 0.82 | CYP3A4 (0.68) | AMY1AKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL28668397 | 0.82 | F2 (0.67) | KDM4EMEN1ALDH1A1TP53CYP3A4 | |
| SCHEMBL7388742 | 0.81 | HDAC6 (0.62) | AMY1AKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL2951540 | 0.81 | ALDH1A1 (0.61) | AMY1AKDM4EMEN1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001066526-A1 | ESTER DERIVATIVES OF DIMETHYLPROPIONIC ACID AND PHARMACETUICAL COMPOSITIONS CONTAINING THEM | CERMOL S.A. (CH) | 2001-09-13 | — | — | WO | disclosed |
| EP-1132381-A1 | Ester derivatives of dimethylpropionic acid and pharmaceutical compositions containing them | CERMOL S.A. (CH) | 2001-09-12 | — | — | EP | disclosed |