Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CCKAR | P32238 | 1/20 | 0.41 |
| ▸ | CCKBR | P32239 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434987 | 0.81 | CYP1A2 (0.66) | CYP1A2 | |
| SCHEMBL5053273 | 0.78 | ADAMTS4 (0.45) | ADAMTS4CCKARCCKBR | |
| SCHEMBL5418068 | 0.76 | CYP1A2 (0.55) | CYP1A2 | |
| SCHEMBL1332798 | 0.74 | ADAMTS4 (0.55) | IDO1ADAMTS4TSHR | |
| SCHEMBL29396939 | 0.74 | ADAMTS4 (0.55) | IDO1ADAMTS4TSHR | |
| SCHEMBL5172404 | 0.74 | ADAMTS4 (0.55) | IDO1ADAMTS4TSHR | |
| SCHEMBL29379275 | 0.74 | ADAMTS4 (0.55) | IDO1ADAMTS4TSHR | |
| SCHEMBL8531397 | 0.73 | CYP1A2 (0.54) | CYP1A2 | |
| SCHEMBL4393088 | 0.73 | ALPI (0.54) | ADAMTS4TSHR | |
| SCHEMBL45382 | 0.73 | ALPI (0.54) | ADAMTS4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993011154-A1 | INHIBITORS OF THE CONVERSION OF BIG ENDOTHELIN TO ENDOTHELIN | BERLEX LABORATORIES, INC. (US) | 1993-06-10 | — | — | WO | disclosed |