Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.74 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 5/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1636984 | 0.85 | MAOA (1.00) | MAOAMAP2K1MAOBKDM1AHTR2C | |
| SCHEMBL6331656 | 0.81 | MAOB (0.52) | MAOAMAP2K1MAOBKDM1AHRH1 | |
| SCHEMBL9359327 | 0.80 | MAOA (0.58) | MAOAMAP2K1MAOBKDM1AKMT2A | |
| SCHEMBL6610340 | 0.78 | MAOA (0.57) | MAOAMAP2K1MAOBKDM1AKMT2A | |
| SCHEMBL31322216 | 0.78 | SLC18A3 (0.53) | MAOAMAOBKDM1AHTR2CHRH1 | |
| SCHEMBL239790 | 0.75 | HTR2C (0.64) | MAOAMAOBKDM1ATDP1HTR2C | |
| Hydrochloric Acid SCHEMBL2800981 | 0.74 | HTR2C (0.65) | MAOAMAOBKDM1ATDP1HTR2C | |
| SCHEMBL6331476 | 0.74 | MAP2K1 (1.00) | MAOAMAP2K1MAOBKMT2A | |
| SCHEMBL7399263 | 0.73 | MAOA (0.51) | MAOAMAP2K1HTR2CKMT2AALDH1A1 | |
| SCHEMBL2084131 | 0.71 | MAPT (0.66) | MAOAMAP2K1MAOBKDM1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5206233-A | Antidepressants, antiischemic agents | WARNER-LAMBERT COMPANY (US) | 1993-04-27 | — | — | US | claimed |
| WO-1993004053-A1 | SUBSTITUTED THIAZEPINES AS CENTRAL NERVOUS SYSTEM AGENTS | WARNER-LAMBERT COMPANY (US) | 1993-03-04 | — | — | WO | claimed |
| US-5206233-A | Antidepressants, antiischemic agents | WARNER-LAMBERT COMPANY (US) | 1993-04-27 | — | — | US | disclosed |
| WO-1993004053-A1 | SUBSTITUTED THIAZEPINES AS CENTRAL NERVOUS SYSTEM AGENTS | WARNER-LAMBERT COMPANY (US) | 1993-03-04 | — | — | WO | disclosed |