Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.57 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9359327 | 0.95 | MAOA (0.58) | MAOAMAP2K1KDM1AMAOBKMT2A | |
| SCHEMBL27621080 | 0.80 | MAOA (0.44) | MAOAMAP2K1KMT2ATSHRKDM4E | |
| SCHEMBL7398210 | 0.79 | KDM4E (0.47) | MAOAMAP2K1KMT2ATSHRKDM4E | |
| SCHEMBL7394236 | 0.78 | MAOA (0.74) | MAOAMAP2K1KDM1AMAOBKMT2A | |
| SCHEMBL6610911 | 0.78 | LTA4H (0.41) | MAOAMAOBKMT2APTGS2ALDH1A1 | |
| SCHEMBL702892 | 0.78 | CYP1A2 (0.43) | MAOAMAP2K1KMT2ATSHR | |
| SCHEMBL7399263 | 0.77 | MAOA (0.51) | MAOAMAP2K1KMT2ATSHRPTGS1 | |
| SCHEMBL1344540 | 0.76 | TSHR (0.50) | MAOAMAP2K1KDM1AMAOBKMT2A | |
| SCHEMBL28207617 | 0.76 | SLC18A3 (0.37) | MAOAKMT2ATSHRALDH1A1DDB1 | |
| SCHEMBL6613526 | 0.76 | ESR2 (0.39) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140895-B1 | THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-03-24 | — | — | EP | disclosed |
| EP-1140895-A2 | THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040576-A2 | THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-13 | — | — | WO | disclosed |