Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.50 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394326 | 0.89 | LTA4H (0.63) | SIGMAR1KCNH2LTA4HHRH3KDM4E | |
| SCHEMBL5281462 | 0.88 | SIGMAR1 (0.63) | SIGMAR1KCNH2LTA4HHRH3HTR7 | |
| SCHEMBL491545 | 0.85 | SIGMAR1 (0.67) | SIGMAR1HTR7HTR1ADRD2HTR2A | |
| SCHEMBL8909943 | 0.84 | ALDH1A1 (0.66) | SIGMAR1HTR7HTR1ADRD2HTR2A | |
| SCHEMBL8909936 | 0.84 | ALDH1A1 (0.66) | SIGMAR1HTR7HTR1ADRD2HTR2A | |
| SCHEMBL5488691 | 0.81 | HRH3 (0.56) | HRH3 | |
| SCHEMBL492189 | 0.81 | KCNH2 (0.71) | SIGMAR1KCNH2LTA4HHRH3ALDH1A1 | |
| SCHEMBL5284021 | 0.81 | LTA4H (0.54) | LTA4HHRH3KDM4E | |
| SCHEMBL8693251 | 0.78 | ALDH1A1 (0.69) | SIGMAR1LTA4HHTR7HTR1ADRD2 | |
| SCHEMBL8910535 | 0.78 | ALDH1A1 (0.69) | SIGMAR1LTA4HHTR7HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100503-A2 | NON-IMIDAZOLE ALKYLAMINES AS HISTAMINE H 3?-RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS | SOCIETE CIVILE BIOPROJET (FR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000006254-A2 | NON-IMIDAZOLE ALKYLAMINES AS HISTAMINE H3-RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS | SOCIETE CIVILE BIOPROJET (FR) | 2000-02-10 | — | — | WO | disclosed |