Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 8/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | RNF4 | P78317 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8179574 | 0.91 | L3MBTL1 (0.40) | KEAP1NFE2L2L3MBTL1STING1MAPT | |
| SCHEMBL8175134 | 0.90 | PPARG (0.44) | L3MBTL1MAPTSMN1; SMN2CNR2RNF4 | |
| SCHEMBL7393894 | 0.82 | DYRK1A (0.42) | KEAP1NFE2L2L3MBTL1STING1DYRK1A | |
| SCHEMBL7394624 | 0.79 | STING1 (0.50) | L3MBTL1STING1MAPTSERPINE1 | |
| SCHEMBL6177057 | 0.79 | SERPINE1 (0.56) | SERPINE1 | |
| SCHEMBL6177204 | 0.76 | POLB (0.36) | KEAP1NFE2L2L3MBTL1MAPTPTGDR2 | |
| SCHEMBL7397312 | 0.76 | FABP4 (0.39) | KEAP1NFE2L2L3MBTL1DYRK1A | |
| SCHEMBL7395385 | 0.76 | L3MBTL1 (0.46) | L3MBTL1STING1MAPTSERPINE1 | |
| SCHEMBL8176254 | 0.76 | L3MBTL1 (0.41) | L3MBTL1STING1MAPTCNR2NPBWR1 | |
| SCHEMBL7395401 | 0.75 | L3MBTL1 (0.51) | L3MBTL1STING1CNR2SERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955299-B1 | Benzothiophene, benzofurane and indole derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-03-13 | — | — | EP | disclosed |
| US-6048875-A | CARDIOVASCULAR DISORDERS; REDUCING THROMBOSIS | ADIR ET COMPAGNIE (FR) | 2000-04-11 | — | — | US | disclosed |
| EP-0955299-A1 | Benzothiophene, benzofurane and indole derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-11-10 | — | — | EP | disclosed |