Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | RNF4 | P78317 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394341 | 0.90 | KEAP1 (0.40) | MAPTSMN1; SMN2L3MBTL1CNR2SERPINE1 | |
| SCHEMBL8179574 | 0.87 | L3MBTL1 (0.40) | MAPTSMN1; SMN2L3MBTL1CNR2SERPINE1 | |
| SCHEMBL7861311 | 0.81 | SERPINE1 (0.54) | SERPINE1 | |
| SCHEMBL8167640 | 0.80 | L3MBTL1 (0.42) | ALDH1A1MAPTTSHRL3MBTL1CNR2 | |
| SCHEMBL7869588 | 0.79 | POLB (0.37) | PPARGALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL8180473 | 0.74 | L3MBTL1 (0.40) | ALDH1A1LMNAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL7394624 | 0.73 | STING1 (0.50) | ALDH1A1MAPTL3MBTL1SERPINE1GAA | |
| SCHEMBL7397312 | 0.73 | FABP4 (0.39) | ALDH1A1TSHRL3MBTL1MEN1KMT2A | |
| SCHEMBL7393894 | 0.72 | DYRK1A (0.42) | L3MBTL1SERPINE1RNF4 | |
| SCHEMBL8176254 | 0.72 | L3MBTL1 (0.41) | PPARGALDH1A1MAPTL3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048875-A | CARDIOVASCULAR DISORDERS; REDUCING THROMBOSIS | ADIR ET COMPAGNIE (FR) | 2000-04-11 | — | — | US | disclosed |