Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PKLR | P30613 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7389758 | 0.86 | GLO1 (0.47) | MEN1KMT2AATMGAAALDH1A1 | |
| SCHEMBL7392579 | 0.79 | F2 (0.45) | ST14F2KMT2AALDH1A1POLB | |
| SCHEMBL6765251 | 0.72 | F2 (0.59) | ST14F2MEN1KMT2AGAA | |
| SCHEMBL6636091 | 0.72 | F2 (0.77) | ST14F2MEN1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL8016170 | 0.71 | F2 (0.63) | ST14F2MEN1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL6640827 | 0.70 | F2 (0.58) | ST14F2MEN1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL6635034 | 0.70 | F2 (0.60) | ST14F2MEN1KMT2AGAA | |
| SCHEMBL7394637 | 0.70 | GLO1 (0.48) | MEN1KMT2AATMGAAALDH1A1 | |
| SCHEMBL852138 | 0.69 | ST14 (1.00) | ST14F2MEN1KMT2AATM | |
| SCHEMBL7395993 | 0.69 | ALDH1A1 (0.37) | F2KMT2AGAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100795-A1 | DISUBSTITUTED BICYCLIC HETEROCYCLES HAVING, IN PARTICULAR, A THROMBIN INHIBITIVE EFFECT | BOEHRINGER INGELHEIM ZENTRALE GMBH (DE) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000008014-A1 | DISUBSTITUTED BICYCLIC HETEROCYCLES HAVING, IN PARTICULAR, A THROMBIN INHIBITIVE EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-02-17 | — | — | WO | disclosed |