Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SLC40A1 | Q9NP59 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.40 |
| ▸ | PKLR | P30613 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7395865 | 0.86 | ST14 (0.53) | MEN1KMT2AATMSLC40A1TSHR | |
| SCHEMBL7394637 | 0.84 | GLO1 (0.48) | GLO1MEN1KMT2AATMSLC40A1 | |
| SCHEMBL7394535 | 0.76 | CKS1B (0.49) | GLO1MEN1KMT2AATMSLC40A1 | |
| SCHEMBL6636395 | 0.71 | F2 (0.58) | GLO1MEN1KMT2AALDH1A1GAA | |
| SCHEMBL6639447 | 0.71 | PKM (0.50) | GLO1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL6572882 | 0.69 | MEN1 (0.52) | GLO1MEN1KMT2AATMALDH1A1 | |
| SCHEMBL852135 | 0.68 | ST14 (0.70) | GLO1MEN1KMT2AATMSLC40A1 | |
| SCHEMBL8016188 | 0.67 | ALDH1A1 (0.49) | GLO1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7391516 | 0.67 | SLC40A1 (0.48) | GLO1MEN1KMT2AATMSLC40A1 | |
| SCHEMBL8026334 | 0.67 | F2 (0.55) | MEN1KMT2AALDH1A1GAABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100795-A1 | DISUBSTITUTED BICYCLIC HETEROCYCLES HAVING, IN PARTICULAR, A THROMBIN INHIBITIVE EFFECT | BOEHRINGER INGELHEIM ZENTRALE GMBH (DE) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000008014-A1 | DISUBSTITUTED BICYCLIC HETEROCYCLES HAVING, IN PARTICULAR, A THROMBIN INHIBITIVE EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-02-17 | — | — | WO | disclosed |