Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.52 |
| ▸ | KDM6B | O15054 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CA9 | Q16790 | 4/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | LATS1 | O95835 | 1/20 | 0.40 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | CISD1 | Q9NZ45 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | BRS3 | P32247 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7358606 | 0.97 | KDM4C (0.56) | KDM4CKDM6BCA12CA1CA2 | |
| SCHEMBL7398435 | 0.84 | CA12 (0.47) | KDM4CKDM6BCA12CA1CA2 | |
| SCHEMBL8562379 | 0.82 | CA2 (0.61) | KDM4CKDM6BCA12CA1CA2 | |
| SCHEMBL11593433 | 0.81 | KDM4C (0.55) | KDM4CKDM6BNAAALATS1LATS2 | |
| SCHEMBL27278463 | 0.78 | L3MBTL1 (0.62) | CA12CA1CA2CA9L3MBTL1 | |
| SCHEMBL7396131 | 0.78 | KDM6B (0.55) | KDM4CKDM6BCA12CA1CA2 | |
| SCHEMBL7360063 | 0.77 | KDM6B (0.59) | KDM4CKDM6BCA12CA1CA2 | |
| SCHEMBL11478702 | 0.77 | KDM4C (0.52) | KDM4CKDM6BL3MBTL1NAAALATS1 | |
| SCHEMBL31299788 | 0.77 | L3MBTL1 (0.64) | CA12CA9L3MBTL1NAAACISD1 | |
| SCHEMBL5648521 | 0.77 | KDM4C (0.72) | KDM4CKDM6BNAAACISD1HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046553-A1 | THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |