Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 4/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.40 |
| ▸ | PRKCG | P05129 | 2/20 | 0.37 |
| ▸ | PRKCB | P05771 | 2/20 | 0.37 |
| ▸ | PRKCH | P24723 | 2/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.35 |
| ▸ | F2 | P00734 | 7/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7406684 | 1.00 | PRKCA (0.40) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL7399369 | 0.83 | ITGB3 (0.42) | PRKCAPRKCDITGB3ITGA2BF2 | |
| SCHEMBL7396167 | 0.83 | PRKCA (0.38) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL7394671 | 0.82 | MAPT (0.44) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL7394811 | 0.82 | MAPT (0.44) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL7394664 | 0.82 | MAPT (0.44) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL7394672 | 0.82 | MAPT (0.44) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL7394809 | 0.82 | MAPT (0.44) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL7398691 | 0.81 | F2 (0.43) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL7400741 | 0.81 | F2 (0.43) | PRKCAPRKCDPRKCGPRKCBPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994000424-A1 | PHENYL AMIDINE ALKANOIC ACIDS AND LACTONES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-01-06 | — | — | WO | claimed |
| US-5646183-A | Phenyl amidine alkanoic acids useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1997-07-08 | — | — | US | disclosed |
| US-5612355-A | Phenyl amidine lactones useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1997-03-18 | — | — | US | disclosed |
| WO-1994000424-A1 | PHENYL AMIDINE ALKANOIC ACIDS AND LACTONES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-01-06 | — | — | WO | disclosed |