Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 4/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.38 |
| ▸ | PRKCG | P05129 | 2/20 | 0.35 |
| ▸ | PRKCB | P05771 | 2/20 | 0.35 |
| ▸ | PRKCH | P24723 | 2/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PLA2G6 | O60733 | 2/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399372 | 0.83 | PRKCA (0.37) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL7406684 | 0.83 | PRKCA (0.40) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL7396164 | 0.83 | PRKCA (0.40) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL7394664 | 0.82 | MAPT (0.44) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL7394809 | 0.82 | MAPT (0.44) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL7394811 | 0.82 | MAPT (0.44) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL7394672 | 0.82 | MAPT (0.44) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL7394671 | 0.82 | MAPT (0.44) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL7400445 | 0.82 | PRKCA (0.40) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL7399119 | 0.82 | PRKCA (0.40) | PRKCAPRKCDPRKCGPRKCBPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994000424-A1 | PHENYL AMIDINE ALKANOIC ACIDS AND LACTONES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-01-06 | — | — | WO | claimed |
| WO-1994000424-A1 | PHENYL AMIDINE ALKANOIC ACIDS AND LACTONES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-01-06 | — | — | WO | disclosed |