Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 4/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.40 |
| ▸ | PRKCG | P05129 | 2/20 | 0.37 |
| ▸ | PRKCB | P05771 | 2/20 | 0.37 |
| ▸ | PRKCH | P24723 | 2/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.37 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PLA2G6 | O60733 | 2/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400445 | 1.00 | PRKCA (0.40) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL7441505 | 0.88 | NAMPT (0.35) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL7396921 | 0.88 | NAMPT (0.35) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL7397355 | 0.84 | PRKCA (0.39) | PRKCAPRKCD | |
| SCHEMBL7404000 | 0.83 | PRKCD (0.38) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL7396167 | 0.82 | PRKCA (0.38) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL7398539 | 0.81 | PRKCA (0.35) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL7399372 | 0.80 | PRKCA (0.37) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL7398691 | 0.80 | F2 (0.43) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL7400741 | 0.80 | F2 (0.43) | PRKCAPRKCDPRKCGPRKCBPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994000424-A1 | PHENYL AMIDINE ALKANOIC ACIDS AND LACTONES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-01-06 | — | — | WO | claimed |
| US-5646183-A | Phenyl amidine alkanoic acids useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1997-07-08 | — | — | US | disclosed |
| US-5612355-A | Phenyl amidine lactones useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1997-03-18 | — | — | US | disclosed |