Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21137668 | 0.83 | ALDH1A1 (0.65) | TDP1ALDH1A1MAPK1L3MBTL1LMNA | |
| SCHEMBL62534 | 0.83 | ALDH1A1 (0.59) | TDP1ALDH1A1MAPK1L3MBTL1LMNA | |
| SCHEMBL11453114 | 0.82 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1MAPTRAB9A | |
| SCHEMBL28257721 | 0.82 | LMNA (0.53) | ALDH1A1MAPK1L3MBTL1LMNAMAPT | |
| SCHEMBL11454434 | 0.82 | ALDH1A1 (0.54) | TDP1ALDH1A1MAPK1L3MBTL1CA12 | |
| Hydrochloric Acid SCHEMBL27368126 | 0.81 | ALDH1A1 (0.58) | TDP1ALDH1A1MAPK1L3MBTL1LMNA | |
| SCHEMBL6560866 | 0.80 | HIF1A (0.56) | FFAR1ALDH1A1KDM4ELMNAMAPT | |
| Methyl 3-Phenylpropanoate SCHEMBL168711 | 0.80 | TDP1 (0.68) | FFAR1TDP1ALDH1A1CA12CA7 | |
| SCHEMBL22338581 | 0.79 | KDM1A (0.57) | ALDH1A1MAPK1KDM4ELMNAMAPT | |
| SCHEMBL11465968 | 0.79 | MEN1 (0.57) | ALDH1A1MAPK1L3MBTL1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587134-A2 | Cyclic urea derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1994-03-16 | — | — | EP | disclosed |