Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.57 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315510 | 0.84 | KDM1A (0.67) | KDM1ARCOR1MAPK1NPSR1HTT | |
| SCHEMBL11925397 | 0.83 | KDM1A (0.64) | KDM1ARCOR1MAPK1NPSR1HTT | |
| SCHEMBL7624965 | 0.82 | KDM1A (0.67) | KDM1ARCOR1MAPK1MAPTNPSR1 | |
| SCHEMBL12059018 | 0.82 | MAPT (0.71) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7758912 | 0.80 | KDM1A (0.64) | KDM1ARCOR1MAPK1MAPTNPSR1 | |
| SCHEMBL17570861 | 0.79 | HTT (0.53) | MAPK1MAPTNPSR1NPBWR1MCHR1 | |
| SCHEMBL7396304 | 0.79 | FFAR1 (0.49) | MAPK1MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL11432703 | 0.79 | ALDH1A1 (0.56) | KDM1ARCOR1MAPK1MAPTNPSR1 | |
| SCHEMBL11437278 | 0.79 | ALDH1A1 (0.56) | KDM1ARCOR1MAPK1MAPTNPSR1 | |
| SCHEMBL3070644 | 0.78 | POLB (0.56) | KDM1ARCOR1MAPTSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163554-A1 | IL-17A MODULATORS AND USES THEREOF | DICE ALPHA, INC. (US) | 2020-08-13 | — | — | WO | disclosed |