Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 4/20 | 0.31 |
| ▸ | RAB9A | P51151 | 4/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397367 | 0.94 | SMN1; SMN2 (0.33) | KDM4ESMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL7392482 | 0.91 | DRD2 (0.35) | KDM4ESMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL7395669 | 0.91 | ALDH1A1 (0.42) | KDM4ESMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL7395085 | 0.86 | ALDH1A1 (0.42) | KDM4ESMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL7394074 | 0.85 | MAPT (0.43) | KDM4ESMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL7394844 | 0.85 | NPC1 (0.37) | KDM4ESMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL7388128 | 0.85 | ITGB3 (0.40) | SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL7392909 | 0.82 | MAPT (0.43) | KDM4ESMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL7386945 | 0.81 | DRD3 (0.38) | KDM4ESMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL7390234 | 0.81 | ITGB3 (0.40) | SMN1; SMN2LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760364-B1 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI CHEMICALS INC (JP) | 2000-07-19 | — | — | EP | disclosed |
| EP-0760364-A2 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1997-03-05 | — | — | EP | disclosed |