Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | HCN1 | O60741 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399966 | 0.86 | HTR3E (0.41) | HTR3EHTR3BHTR3AHTR4HTR3D | |
| SCHEMBL7395588 | 0.84 | HTR3E (0.44) | HTR3EHTR3BHTR3AHTR4HTR3D | |
| SCHEMBL7396628 | 0.83 | HTR4 (0.65) | HTR3EHTR3BHTR3AHTR4HTR3D | |
| SCHEMBL7392392 | 0.81 | HTR3A (0.49) | HTR3EHTR3BHTR3AHTR4HTR3D | |
| SCHEMBL7398975 | 0.81 | HTR3E (0.42) | HTR3EHTR3BHTR3AHTR4HTR3D | |
| SCHEMBL7394948 | 0.78 | HTR3E (0.60) | HTR3EHTR3BHTR3AHTR4HTR3D | |
| SCHEMBL7430400 | 0.70 | PARP1 (0.51) | HTR3EHTR3BHTR3AHTR4HTR3D | |
| Fumaric Acid SCHEMBL7396244 | 0.70 | HTR3E (0.61) | HTR3EHTR3BHTR3AHTR4HTR3D | |
| Fumaric Acid SCHEMBL7396248 | 0.70 | HTR3E (0.61) | HTR3EHTR3BHTR3AHTR4HTR3D | |
| SCHEMBL7392520 | 0.69 | HTR4 (0.55) | HTR3EHTR3BHTR3AHTR4HTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691341-A1 | Benzopyrancarboxamide derivatives, salt thereof, process for the preparation of same and use thereof | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1996-01-10 | — | — | EP | disclosed |