Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | TNF | P01375 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397382 | 1.00 | NOD1 (0.45) | NOD1RAB9ATNFNPC1MEN1 | |
| Hydrochloric Acid SCHEMBL7393599 | 0.99 | NOD1 (0.45) | NOD1RAB9ATNFNPC1MEN1 | |
| Hydrochloric Acid SCHEMBL7393598 | 0.99 | NOD1 (0.45) | NOD1RAB9ATNFNPC1MEN1 | |
| SCHEMBL7396800 | 0.97 | ITGB3 (0.49) | NOD1RAB9ATNFNPC1MEN1 | |
| SCHEMBL7396801 | 0.97 | ITGB3 (0.49) | NOD1RAB9ATNFNPC1MEN1 | |
| SCHEMBL7393412 | 0.95 | ITGB3 (0.43) | NOD1RAB9ATNFNPC1MEN1 | |
| SCHEMBL7393407 | 0.95 | ITGB3 (0.43) | NOD1RAB9ATNFNPC1MEN1 | |
| SCHEMBL7396215 | 0.95 | ALDH1A1 (0.46) | NOD1RAB9ATNFNPC1MEN1 | |
| SCHEMBL7396213 | 0.95 | ALDH1A1 (0.46) | NOD1RAB9ATNFNPC1MEN1 | |
| SCHEMBL7389172 | 0.94 | ITGB3 (0.46) | NOD1RAB9ATNFNPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760364-B1 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI CHEMICALS INC (JP) | 2000-07-19 | — | — | EP | disclosed |
| EP-0760364-A2 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1997-03-05 | — | — | EP | disclosed |