Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 8/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 8/20 | 0.39 |
| ▸ | GSK3B | P49841 | 3/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.38 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL7400191 | 0.96 | ACKR3 (0.40) | ACKR3KMT2AHCRTR1HCRTR2GSK3B | |
| Maleic Acid SCHEMBL7400186 | 0.96 | ACKR3 (0.40) | ACKR3KMT2AHCRTR1HCRTR2GSK3B | |
| SCHEMBL7403466 | 0.89 | ACKR3 (0.40) | ACKR3KMT2AHCRTR1HCRTR2 | |
| SCHEMBL7399469 | 0.88 | ACKR3 (0.40) | ACKR3KMT2AHCRTR1HCRTR2 | |
| SCHEMBL7397799 | 0.86 | ACHE (0.46) | BCHE | |
| SCHEMBL8134001 | 0.86 | SLC6A2 (0.38) | ACKR3KMT2AHCRTR1HCRTR2KDM4E | |
| SCHEMBL7398676 | 0.84 | KDM1A (0.40) | ACKR3KMT2AHCRTR1HCRTR2 | |
| SCHEMBL7398566 | 0.84 | HCRTR1 (0.35) | ACKR3KMT2AHCRTR1HCRTR2 | |
| SCHEMBL8836846 | 0.84 | HCRTR1 (0.35) | ACKR3KMT2AHCRTR1HCRTR2 | |
| SCHEMBL1039396 | 0.84 | HTR4 (0.40) | ACKR3KMT2AHCRTR1HCRTR2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3236298-B2 | — | — | 2001-12-10 | — | — | JP | claimed |
| EP-0640081-B1 | SUBSTITUTED PHENYLCARBAMATES AND PHENYLUREAS, THEIR PREPARATION AND THEIR USE AS 5-HT4 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2000-01-12 | — | — | EP | claimed |
| US-5618827-A | TREATING GASTROINTESTINAL, URINARY, CARDIOVASCULAR, CENTRAL NERVOUS SYTEM DISORDERS | GLAXO GROUP LIMITED (GB) | 1997-04-08 | — | — | US | claimed |
| EP-0640081-A1 | SUBSTITUTED PHENYLCARBAMATES AND PHENYLUREAS, THEIR PREPARATION AND THEIR USE AS 5-HT ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1995-03-01 | — | — | EP | claimed |
| WO-1993020071-A1 | SUBSTITUTED PHENYLCARBAMATES AND PHENYLUREAS, THEIR PREPARATION AND THEIR USE AS 5-HT ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1993-10-14 | — | — | WO | claimed |
| US-5618827-A | TREATING GASTROINTESTINAL, URINARY, CARDIOVASCULAR, CENTRAL NERVOUS SYTEM DISORDERS | GLAXO GROUP LIMITED (GB) | 1997-04-08 | — | — | US | disclosed |