Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 4/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1039396 | 0.93 | HTR4 (0.40) | HCRTR1HCRTR2ACKR3KMT2AGFER | |
| SCHEMBL8141472 | 0.90 | OPRK1 (0.40) | OPRK1KCNH2HRH1OPRM1 | |
| SCHEMBL7398680 | 0.89 | HCRTR1 (0.35) | HCRTR1HCRTR2ACKR3OPRK1KMT2A | |
| SCHEMBL7399420 | 0.89 | HTT (0.37) | HCRTR1HCRTR2ACKR3KMT2AKCNH2 | |
| SCHEMBL7397093 | 0.88 | KDM1A (0.39) | HCRTR1HCRTR2ACKR3OPRK1KMT2A | |
| SCHEMBL8134001 | 0.88 | SLC6A2 (0.38) | HCRTR1HCRTR2ACKR3KMT2AKCNH2 | |
| SCHEMBL7403466 | 0.86 | ACKR3 (0.40) | HCRTR1HCRTR2ACKR3KMT2AKCNH2 | |
| SCHEMBL7402277 | 0.86 | MAPT (0.42) | KCNH2KDM1A | |
| Fumaric Acid SCHEMBL7399492 | 0.86 | HCRTR1 (0.33) | HCRTR1HCRTR2ACKR3OPRK1KMT2A | |
| Maleic Acid SCHEMBL7399489 | 0.86 | HCRTR1 (0.33) | HCRTR1HCRTR2ACKR3OPRK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618827-A | TREATING GASTROINTESTINAL, URINARY, CARDIOVASCULAR, CENTRAL NERVOUS SYTEM DISORDERS | GLAXO GROUP LIMITED (GB) | 1997-04-08 | — | — | US | disclosed |