Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PAM | P19021 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6566174 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MAPK1L3MBTL1PAMHCAR2 | |
| SCHEMBL7587208 | 0.74 | ALDH1A1 (0.47) | ALDH1A1MAPK1L3MBTL1HCAR2SLC6A2 | |
| SCHEMBL6271777 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MAPK1L3MBTL1HCAR2SLC6A2 | |
| SCHEMBL27739393 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MAPK1L3MBTL1HCAR2SLC6A2 | |
| SCHEMBL11330873 | 0.71 | ALDH1A1 (0.48) | ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3 | |
| SCHEMBL30803699 | 0.71 | ALDH1A1 (0.44) | ALDH1A1MAPK1L3MBTL1HCAR2SLC6A2 | |
| SCHEMBL8592588 | 0.71 | ALDH1A1 (0.40) | ALDH1A1MAPK1L3MBTL1HCAR2SLC6A2 | |
| SCHEMBL5370663 | 0.70 | ALDH1A1 (0.43) | ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3 | |
| SCHEMBL8740511 | 0.70 | SLC1A3 (0.41) | ALDH1A1MAPK1L3MBTL1HCAR2SLC6A2 | |
| SCHEMBL6951407 | 0.70 | HTT (0.44) | ALDH1A1MAPK1HCAR2SLC6A3KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994013636-A1 | NEW SUBSTITUTED AZETIDINONES AS ANTI-INFLAMMATORY AND ANTIDEGENERATIVE AGENTS | MERCK & CO., INC. (US) | 1994-06-23 | — | — | WO | disclosed |
| EP-0144103-B1 | Methods and compositions for preparation of H-ARG-X-Z-Y-TYR-R | ORTHO PHARMA CORP (US) | 1993-12-29 | — | — | EP | disclosed |
| EP-0144103-A2 | Methods and compositions for preparation of H-ARG-X-Z-Y-TYR-R | ORTHO PHARMACEUTICAL CORPORATION (US) | 1985-06-12 | — | — | EP | disclosed |