Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | PAM | P19021 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8740511 | 0.87 | SLC1A3 (0.41) | ALDH1A1MAPK1L3MBTL1HCAR2KMT2A | |
| SCHEMBL11436323 | 0.87 | ALDH1A1 (0.47) | ALDH1A1MAPK1L3MBTL1HCAR2KMT2A | |
| SCHEMBL8592588 | 0.86 | ALDH1A1 (0.40) | ALDH1A1MAPK1L3MBTL1HCAR2KMT2A | |
| SCHEMBL6951407 | 0.83 | HTT (0.44) | ALDH1A1MAPK1HCAR2SLC6A3FFAR1 | |
| SCHEMBL8323870 | 0.83 | ALDH1A1 (0.40) | ALDH1A1HCAR2KMT2AMEN1NPC1 | |
| SCHEMBL7398207 | 0.82 | ALDH1A1 (0.45) | ALDH1A1MAPK1L3MBTL1HCAR2KMT2A | |
| SCHEMBL2906610 | 0.81 | HDAC3 (0.46) | ALDH1A1MAPK1SLC6A3FFAR1FFAR4 | |
| SCHEMBL8960248 | 0.80 | TSHR (0.41) | ALDH1A1L3MBTL1HCAR2MAOBTSHR | |
| SCHEMBL8622951 | 0.80 | ALOX5 (0.48) | MAPK1L3MBTL1SLC6A3FFAR1FFAR4 | |
| SCHEMBL8495462 | 0.79 | CCR6 (0.38) | ALDH1A1MAPK1L3MBTL1HCAR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456186-A1 | NOVEL INHIBITOR COMPOUNDS SPECIFIC OF SECRETED NON-PANCREATIC HUMAN A SB 2 /SB PHOSPHOLIPASE OF GROUP II | Yang Ji Chemical Company Ltd. (KR) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003048139-A1 | NOVEL INHIBITOR COMPOUNDS SPECIFIC OF SECRETED NON-PANCREATIC HUMAN A2 PHOSPHOLIPASE OF GROUP II | YANG JI CHEMICAL COMPANY LTD. (KR) | 2003-06-12 | — | — | WO | disclosed |