Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6566174 | 0.87 | ALDH1A1 (0.44) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL11436323 | 0.84 | ALDH1A1 (0.47) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL8592588 | 0.83 | ALDH1A1 (0.40) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL8323870 | 0.80 | ALDH1A1 (0.40) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL28524418 | 0.78 | AGXT (0.44) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL8960248 | 0.78 | TSHR (0.41) | ALDH1A1HCAR2L3MBTL1IDO1 | |
| SCHEMBL6951407 | 0.77 | HTT (0.44) | ALDH1A1NPC1RAB9AHCAR2MAPK1 | |
| SCHEMBL8495462 | 0.77 | CCR6 (0.38) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL10473639 | 0.77 | CARM1 (0.41) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL1573556 | 0.76 | TSHR (0.40) | ALDH1A1L3MBTL1LMNAIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697415-A | Techniques for preventing or treating infections | 拜尔哈文制药股份有限公司 | 2023-02-03 | — | — | CN | disclosed |
| US-5629285-A | Inhibitors of TNF-α secretion | IMMUNEX CORPORATION (US) | 1997-05-13 | — | — | US | disclosed |
| EP-0715619-A4 | INHIBITORS OF TNF-ALPHA SECRETION | IMMUNEX CORP (US) | 1997-03-19 | — | — | EP | disclosed |
| US-5594106-A | Inhibitors of TNF-α secretion | IMMUNEX CORPORATION (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0715619-A1 | INHIBITORS OF TNF-ALPHA SECRETION | IMMUNEX CORPORATION (US) | 1996-06-12 | — | — | EP | disclosed |
| WO-1995006031-A1 | INHIBITORS OF TNF-ALPHA SECRETION | IMMUNEX CORPORATION (US) | 1995-03-02 | — | — | WO | disclosed |