Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
| ▸ | GABRE | P78334 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7395672 | 0.99 | MEN1 (0.46) | MEN1GABRPGABRDALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL7392937 | 0.90 | MEN1 (0.46) | MEN1GABRPGABRDALDH1A1CYP1A2 | |
| SCHEMBL7398879 | 0.89 | GABRP (0.49) | MEN1GABRPGABRDALDH1A1CYP1A2 | |
| SCHEMBL7393855 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL7391492 | 0.88 | GABRP (0.49) | MEN1GABRPGABRDALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL8871952 | 0.86 | GABRP (0.46) | MEN1GABRPGABRDALDH1A1CYP1A2 | |
| SCHEMBL7393977 | 0.85 | GABRG2 (0.47) | MEN1GABRPGABRDALDH1A1CYP1A2 | |
| SCHEMBL7393030 | 0.85 | MEN1 (0.52) | MEN1GABRPGABRDALDH1A1CYP1A2 | |
| SCHEMBL7307204 | 0.85 | MEN1 (0.55) | MEN1GABRPGABRDALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL7396463 | 0.85 | GABRG2 (0.46) | MEN1GABRPGABRDALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672666-B1 | Imidazodiazepins | HOFFMANN LA ROCHE (CH) | 2001-07-25 | — | — | EP | disclosed |
| US-5665718-A | ANXIOLYTIC, ANTICONVULSANT, MUSCLE RELAXANT, SEDATIVE, HYPNOTIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1997-09-09 | — | — | US | disclosed |
| EP-0672666-A2 | Imidazodiazepins | F. Hoffmann-La Roche AG (CH) | 1995-09-20 | — | — | EP | disclosed |