Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 13/20 | 1.00 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7389210 | 0.94 | MMP3 (0.90) | MMP3SMPD1MAPTL3MBTL1HDAC3 | |
| SCHEMBL7396841 | 0.91 | MMP3 (0.83) | MMP3SMPD1 | |
| SCHEMBL7993490 | 0.87 | MMP3 (0.78) | MMP3MAPTTAAR1 | |
| SCHEMBL7991540 | 0.86 | MMP3 (0.76) | MMP3MAPTL3MBTL1TAAR1 | |
| SCHEMBL7978894 | 0.85 | MMP3 (0.74) | MMP3 | |
| SCHEMBL7996980 | 0.82 | MMP3 (0.69) | MMP3MAPTL3MBTL1TAAR1HDAC3 | |
| SCHEMBL9348237 | 0.81 | MMP3 (0.69) | MMP3MAPTL3MBTL1TAAR1 | |
| SCHEMBL7996795 | 0.80 | MMP3 (0.66) | MMP3MAPTL3MBTL1 | |
| SCHEMBL7386826 | 0.79 | MMP3 (1.00) | MMP3 | |
| SCHEMBL7990504 | 0.75 | MMP3 (1.00) | MMP3HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | claimed |
| WO-2000037433-A1 | INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 2000-06-29 | — | — | WO | claimed |