Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 4/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7993490 | 0.80 | MMP3 (0.78) | MMP3TDP1BCL2MAPTMCL1 | |
| SCHEMBL7398557 | 0.80 | MMP3 (1.00) | MMP3L3MBTL1MAPT | |
| SCHEMBL7991540 | 0.79 | MMP3 (0.76) | MMP3L3MBTL1TDP1BCL2MAPT | |
| SCHEMBL9348237 | 0.76 | MMP3 (0.69) | MMP3L3MBTL1TDP1MAPTMCL1 | |
| SCHEMBL7996980 | 0.74 | MMP3 (0.69) | MMP3L3MBTL1TDP1KCNH2MAPT | |
| SCHEMBL7389210 | 0.74 | MMP3 (0.90) | MMP3L3MBTL1MAPTMCL1 | |
| SCHEMBL7399254 | 0.73 | MMP3 (0.43) | MMP3L3MBTL1TDP1POLBRXFP1 | |
| SCHEMBL7399256 | 0.73 | MMP3 (0.43) | MMP3L3MBTL1TDP1POLBRXFP1 | |
| SCHEMBL7396841 | 0.71 | MMP3 (0.83) | MMP3MCL1 | |
| SCHEMBL13321690 | 0.70 | MEN1 (0.39) | MMP3KCNH2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | disclosed |