SCHEMBL9348237

SCHEMBL9348237

O=C(O)C(=O)c1c(CCOc2ccc(Cl)cc2)ccc2ccccc12

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 4/20 0.69
TAAR1 Q96RJ0 1/20 0.45
MCL1 Q07820 2/20 0.44
PTGDR2 Q9Y5Y4 2/20 0.43
MAPT P10636 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PLA2G4A P47712 1/20 0.41
FFAR1 O14842 2/20 0.39
MTNR1A P48039 1/20 0.39
MTNR1B P49286 1/20 0.39
AKR1B1 P15121 1/20 0.39
FFAR4 Q5NUL3 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
CPT2 P23786 1/20 0.39
CPT1A P50416 1/20 0.39
CPT1B Q92523 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9344540 0.91 MMP3 (0.56) MMP3MCL1FFAR1MTNR1AMTNR1B
SCHEMBL9345664 0.88 MMP3 (0.54) MMP3MCL1MAPTL3MBTL1FFAR1
SCHEMBL7993490 0.87 MMP3 (0.78) MMP3TAAR1MCL1PTGDR2MAPT
SCHEMBL7991540 0.83 MMP3 (0.76) MMP3TAAR1MCL1PTGDR2MAPT
SCHEMBL7398557 0.81 MMP3 (1.00) MMP3TAAR1MAPTL3MBTL1
SCHEMBL7996980 0.81 MMP3 (0.69) MMP3TAAR1MCL1PTGDR2MAPT
SCHEMBL7996795 0.76 MMP3 (0.66) MMP3MCL1MAPTTDP1L3MBTL1
SCHEMBL7389210 0.76 MMP3 (0.90) MMP3MCL1MAPTL3MBTL1
SCHEMBL7978894 0.75 MMP3 (0.74) MMP3MCL1PPARGMTNR1AMTNR1B
SCHEMBL7396841 0.73 MMP3 (0.83) MMP3MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0357409-B1 Heat-sensitive recording material FUJI PHOTO FILM CO LTD (JP) 1994-07-20 EP disclosed
EP-0357409-A2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1990-03-07 EP disclosed