SCHEMBL7398570

SCHEMBL7398570

CC(C(N)=O)N(C)Cc1ccc(OCc2ccccc2Cl)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 7/20 0.61
MAOA P21397 3/20 0.53
NR4A2 P43354 2/20 0.51
HTT P42858 2/20 0.47
LMNA P02545 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
SCN9A Q15858 1/20 0.47
MAPT P10636 2/20 0.46
TP53 P04637 1/20 0.46
GAA P10253 1/20 0.46
ADAM17 P78536 1/20 0.45
FFAR1 O14842 1/20 0.45
FFAR4 Q5NUL3 1/20 0.45
RAD52 P43351 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
RAB9A P51151 2/20 0.44
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9129282 1.00 MAOB (0.61) MAOBMAOANR4A2HTTLMNA
SCHEMBL1071203 0.84 MAOB (0.58) MAOBMAOAMEN1KMT2AFFAR1
SCHEMBL9126134 0.83 MAOB (0.53) MAOBMAOAMEN1KMT2AMAPT
SCHEMBL9516428 0.83 MAOB (0.53) MAOBMAOAMEN1KMT2AMAPT
SCHEMBL8935297 0.82 MAOB (0.59) MAOBMAOANR4A2HTTLMNA
SCHEMBL2020147 0.81 MAOB (0.62) MAOBMAOAFFAR1
SCHEMBL2020148 0.81 MAOB (0.62) MAOBMAOAFFAR1
SCHEMBL2185703 0.79 MAOB (0.53) MAOBMAOANR4A2HTTLMNA
SCHEMBL8935286 0.78 MAOB (0.54) MAOBMAOANR4A2HTTLMNA
SCHEMBL2185706 0.78 SCN9A (0.59) MAOBMAOANR4A2SCN9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0400495-B1 N-phenylalkyl substituted alpha-amino carboxamide derivatives and process for their preparation. ERBA CARLO SPA (IT) 1993-11-03 EP disclosed
EP-0426816-A1 N-PHENYLALKYL SUBSTITUTED $g(a)-AMINO CARBOXAMIDE DERIVATIVES AND PROCESS FOR THEIR PREPARATION FARMITALIA CARLO ERBA S.r.l. (IT) 1991-05-15 EP disclosed
EP-0400495-A1 N-phenylalkyl substituted alfa-amino carboxamide derivatives and process for their preparation FARMITALIA CARLO ERBA S.r.l. (IT) 1990-12-05 EP disclosed
WO-1990014334-A1 N-PHENYLALKYL SUBSTITUTED α-AMINO CARBOXAMIDE DERIVATIVES AND PROCESS FOR THEIR PREPARATION FARMITALIA CARLO ERBA S.R.L. (IT) 1990-11-29 WO disclosed