Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935297 | 0.88 | MAOB (0.59) | MAOBMAOANR4A2SMN1; SMN2HTT | |
| SCHEMBL8935310 | 0.86 | MAOB (0.55) | MAOBSLC1A5 | |
| SCHEMBL8935348 | 0.84 | MAOB (0.58) | MAOBMAOAGAAALDH1A1MEN1 | |
| SCHEMBL8935296 | 0.81 | ALOX5 (0.60) | MAOBMAOA | |
| SCHEMBL8935232 | 0.79 | FFAR1 (0.51) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL9129282 | 0.78 | MAOB (0.61) | MAOBMAOANR4A2SMN1; SMN2HTT | |
| SCHEMBL7398570 | 0.78 | MAOB (0.61) | MAOBMAOANR4A2SMN1; SMN2HTT | |
| SCHEMBL7394825 | 0.77 | MAOB (0.54) | MAOBMAOANR4A2SMN1; SMN2HTT | |
| SCHEMBL9130157 | 0.77 | MAOB (0.54) | MAOBMAOANR4A2SMN1; SMN2HTT | |
| SCHEMBL8935251 | 0.76 | MAOB (0.58) | MAOBMAOANR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |