Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9126134 | 1.00 | MAOB (0.53) | MAOBALOX5PTGS1PTGS2MEN1 | |
| SCHEMBL1071203 | 0.96 | MAOB (0.58) | MAOBALOX5PTGS1PTGS2MEN1 | |
| SCHEMBL17372647 | 0.84 | KMT2A (0.55) | MEN1KMT2AALDH1A1 | |
| SCHEMBL19182844 | 0.84 | KMT2A (0.55) | MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL4649930 | 0.83 | LTB4R (0.60) | MAOBALOX5FFAR1PARP10 | |
| SCHEMBL7398570 | 0.83 | MAOB (0.61) | MAOBMEN1KMT2AFFAR1MAPT | |
| SCHEMBL9129282 | 0.83 | MAOB (0.61) | MAOBMEN1KMT2AFFAR1MAPT | |
| Hydrochloric Acid SCHEMBL6529136 | 0.82 | KMT2A (0.54) | MEN1KMT2AALDH1A1 | |
| SCHEMBL2020147 | 0.82 | MAOB (0.62) | MAOBALOX5FFAR1MAOA | |
| SCHEMBL2020148 | 0.82 | MAOB (0.62) | MAOBALOX5FFAR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0400495-B1 | N-phenylalkyl substituted alpha-amino carboxamide derivatives and process for their preparation. | ERBA CARLO SPA (IT) | 1993-11-03 | — | — | EP | disclosed |