⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11085208 | 0.73 | ACHE (0.37) | — | |
| SCHEMBL10616675 | 0.73 | ALDH1A1 (0.34) | — | |
| SCHEMBL6912661 | 0.73 | TSHR (0.33) | — | |
| SCHEMBL28059216 | 0.73 | — | — | |
| SCHEMBL8179330 | 0.71 | ALDH1A1 (0.42) | — | |
| SCHEMBL1375882 | 0.70 | KMT2A (0.36) | — | |
| SCHEMBL8042343 | 0.70 | KDM4E (0.44) | — | |
| SCHEMBL535963 | 0.70 | — | — | |
| SCHEMBL88855 | 0.67 | ALDH1A1 (0.33) | — | |
| SCHEMBL16945780 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846127-A1 | ACYLATED OLIGOPEPTIDE DERIVATIVES HAVING CELL SIGNAL INHIBITING ACTIVITY | Novartis AG (CH) | 1998-06-10 | — | — | EP | disclosed |
| WO-1997008193-A1 | ACYLATED OLIGOPEPTIDE DERIVATIVES HAVING CELL SIGNAL INHIBITING ACTIVITY | NOVARTIS AG (CH) | 1997-03-06 | — | — | WO | disclosed |
| WO-1997007131-A1 | ACYLATED OLIGOPEPTIDES CONTAINING PHOSPHOTYROSINE AS INHIBITORS OF PROTEIN TYROSINE KINASES | NOVARTIS AG (CH) | 1997-02-27 | — | — | WO | disclosed |