Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | CHKA | P35790 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | NCF1 | P14598 | 1/20 | 0.47 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.47 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.46 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.46 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.46 |
| ▸ | KHK | P50053 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9723025 | 0.87 | DRD2 (0.68) | DRD2DRD3MEN1KMT2AOPRM1 | |
| SCHEMBL7589729 | 0.80 | ADRA2C (0.62) | CHKAAOC3ADRB2NCF1PLD1 | |
| SCHEMBL17144785 | 0.79 | MEN1 (0.60) | DRD2DRD3MEN1KMT2AOPRM1 | |
| SCHEMBL29774627 | 0.79 | MEN1 (0.60) | DRD2DRD3MEN1KMT2AOPRM1 | |
| SCHEMBL7334978 | 0.79 | CHKA (0.61) | DRD2DRD3CHKAMEN1KMT2A | |
| SCHEMBL1599836 | 0.79 | MEN1 (0.60) | DRD2DRD3MEN1KMT2AOPRM1 | |
| SCHEMBL29914690 | 0.79 | MEN1 (0.60) | DRD2DRD3MEN1KMT2AOPRM1 | |
| SCHEMBL17644142 | 0.79 | CHKA (0.52) | CHKAAOC3ADRB2NCF1PLD1 | |
| SCHEMBL18590696 | 0.78 | CHKA (0.67) | CHKAADRB2NCF1PLD1KHK | |
| SCHEMBL12525660 | 0.78 | AOC3 (0.57) | DRD2DRD3CHKAAOC3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563141-A | INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |