Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 3/20 | 0.38 |
| ▸ | METAP1 | P53582 | 3/20 | 0.38 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.36 |
| ▸ | KDM4A | O75164 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.36 |
| ▸ | TET3 | O43151 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398943 | 1.00 | OR51E2 (0.40) | OR51E2TP53SMN1; SMN2METAP2METAP1 | |
| SCHEMBL7442197 | 0.80 | — | — | |
| SCHEMBL724401 | 0.80 | — | — | |
| SCHEMBL10633598 | 0.78 | APEX1 (0.41) | TP53METAP2METAP1RNPEPSLC7A5 | |
| SCHEMBL10633609 | 0.78 | APEX1 (0.41) | TP53METAP2METAP1RNPEPSLC7A5 | |
| Carbamic Acid SCHEMBL28209462 | 0.77 | METAP2 (0.41) | METAP2METAP1RNPEPSLC7A5 | |
| SCHEMBL23085771 | 0.74 | SLC7A5 (0.54) | METAP2METAP1SLC7A5 | |
| SCHEMBL2128359 | 0.74 | SLC7A5 (0.54) | METAP2METAP1SLC7A5 | |
| SCHEMBL4955415 | 0.74 | GPR84 (0.43) | OR51E2TP53SMN1; SMN2METAP2METAP1 | |
| SCHEMBL7446893 | 0.74 | GPR84 (0.43) | OR51E2TP53SMN1; SMN2METAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535042-B1 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS | FISONS PLC (GB) | 1995-03-29 | — | — | EP | disclosed |
| US-5348978-A | Angiotensin converting enzyme inhibitors | FISONS PLC (GB) | 1994-09-20 | — | — | US | disclosed |
| EP-0535042-A1 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS. | FISONS PLC (GB) | 1993-04-07 | — | — | EP | disclosed |
| WO-1992000276-A2 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS | FISONS PLC (GB) | 1992-01-09 | — | — | WO | disclosed |