Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCD | Q05655 | 7/20 | 0.38 |
| ▸ | PRKCA | P17252 | 6/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PRKCG | P05129 | 4/20 | 0.34 |
| ▸ | PRKCB | P05771 | 4/20 | 0.34 |
| ▸ | PRKCH | P24723 | 4/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397355 | 0.87 | PRKCA (0.39) | PRKCDPRKCAPPARG | |
| SCHEMBL7398539 | 0.84 | PRKCA (0.35) | PRKCDPRKCAPPARGPRKCGPRKCB | |
| SCHEMBL7400445 | 0.83 | PRKCA (0.40) | PRKCDPRKCAPRKCGPRKCBPRKCH | |
| SCHEMBL7399119 | 0.83 | PRKCA (0.40) | PRKCDPRKCAPRKCGPRKCBPRKCH | |
| SCHEMBL7392204 | 0.83 | PRKCA (0.36) | PRKCDPRKCAPPARGPRKCGPRKCB | |
| SCHEMBL7399372 | 0.82 | PRKCA (0.37) | PRKCDPRKCAPPARGPRKCGPRKCB | |
| SCHEMBL7396167 | 0.79 | PRKCA (0.38) | PRKCDPRKCAPRKCGPRKCBPRKCH | |
| SCHEMBL7398400 | 0.79 | CYP1A2 (0.38) | PRKCDPRKCAPPARGPRKCGPRKCB | |
| SCHEMBL7403999 | 0.78 | PRKCA (0.41) | PRKCDPRKCAPPARGPRKCGPRKCB | |
| SCHEMBL7398589 | 0.78 | PRKCA (0.41) | PRKCDPRKCAPPARGPRKCGPRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646183-A | Phenyl amidine alkanoic acids useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1997-07-08 | — | — | US | disclosed |
| US-5612355-A | Phenyl amidine lactones useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1997-03-18 | — | — | US | disclosed |
| WO-1994000424-A1 | PHENYL AMIDINE ALKANOIC ACIDS AND LACTONES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-01-06 | — | — | WO | disclosed |