Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 8/20 | 0.91 |
| ▸ | HTR3A | P46098 | 2/20 | 0.91 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.91 |
| ▸ | HTR3B | O95264 | 1/20 | 0.91 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.91 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.91 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430663 | 0.95 | HTR4 (1.00) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL7395407 | 0.85 | HTR4 (0.67) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL7393297 | 0.85 | HTR3E (0.67) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL7393687 | 0.84 | HTR4 (0.74) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL7393254 | 0.83 | HTR3A (0.67) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL7436075 | 0.83 | HTR4 (0.72) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL7434513 | 0.81 | HTR4 (0.67) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL2800097 | 0.81 | HTR4 (0.69) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| Fumaric Acid SCHEMBL7394288 | 0.81 | HTR4 (0.61) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| Fumaric Acid SCHEMBL7394291 | 0.81 | HTR4 (0.61) | HTR4HTR3AHTR3EHTR3BHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691341-A1 | Benzopyrancarboxamide derivatives, salt thereof, process for the preparation of same and use thereof | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1996-01-10 | — | — | EP | claimed |
| JP-8073463-A | — | — | None | — | — | JP | disclosed |
| JP-H0873463-A | BENZOPYRANE CARBOXAMIDE DERIVATIVE, ITS SALT AND PRODUCTION METHOD AND USE | SANWA KAGAKU KENKYUSHO CO LTD | 1996-03-19 | — | — | JP | disclosed |
| EP-0691341-A1 | Benzopyrancarboxamide derivatives, salt thereof, process for the preparation of same and use thereof | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1996-01-10 | — | — | EP | disclosed |