Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.51 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | GUSB | P08236 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | THRB | P10828 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.49 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394125 | 0.86 | AMY1A (0.54) | HPSEMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7397419 | 0.84 | KDM4E (0.52) | HPSEMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7394598 | 0.80 | MAPT (0.54) | HPSEMAPTRECQLBLMTDP1 | |
| SCHEMBL7391707 | 0.79 | GUSB (0.71) | HPSEMAPTRECQLBLMTDP1 | |
| SCHEMBL7389936 | 0.78 | KDM4E (0.62) | HPSEMAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7395552 | 0.78 | PARP1 (0.59) | HPSEMAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7402117 | 0.78 | KDM4E (0.61) | MAPTRECQLALDH1A1MEN1KMT2A | |
| SCHEMBL22488596 | 0.76 | AMY1A (0.53) | HPSEMAPTRECQLBLMTDP1 | |
| SCHEMBL7396331 | 0.76 | KDM4E (0.53) | MAPTALDH1A1NPSR1SMN1; SMN2HTT | |
| SCHEMBL7400340 | 0.75 | ALOX5 (0.59) | HPSEALDH1A1GUSBTHRBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1132381-A1 | Ester derivatives of dimethylpropionic acid and pharmaceutical compositions containing them | CERMOL S.A. (CH) | 2001-09-12 | — | — | EP | claimed |
| WO-2001066526-A1 | ESTER DERIVATIVES OF DIMETHYLPROPIONIC ACID AND PHARMACETUICAL COMPOSITIONS CONTAINING THEM | CERMOL S.A. (CH) | 2001-09-13 | — | — | WO | disclosed |
| EP-1132381-A1 | Ester derivatives of dimethylpropionic acid and pharmaceutical compositions containing them | CERMOL S.A. (CH) | 2001-09-12 | — | — | EP | disclosed |